Herpes simplex virus-2 associated with a large fungating penile mass

Herpes simplex virus-2 associated with a large fungating penile mass

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A 48-year-old male with HIV/AIDS presented with an enlarging nodular lesion on the base of his retro doublewide penis.Histology revealed changes consistent with chronic viral infection and culture grew herpes simplex virus 2 (HSV-2).The lesion was refractory to valacyclovir and intralesional (IL) cidofovir therapy.

Urology whirlwind multi selector excised the mass and the defect was repaired primarily with good cosmetic result.Post-operative pathology confirmed HSV-2 despite the unusual appearance of the lesion consisting of nodular mass without gross ulceration.